Effect of Vitamin E-Deficiency on Protein Synthesis in Skeletal Muscle of the Rabbit
| Autor: | J. F. Diehl, L. L. Sanders |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Muscle Proteins Biology General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Internal medicine medicine Protein biosynthesis Animals Vitamin E Deficiency Muscle Skeletal Vitamin E Acetate Differential centrifugation Vitamin E Proteins Skeletal muscle Vitamins medicine.anatomical_structure Endocrinology chemistry Protein Biosynthesis Specific activity Rabbits Vitamin E deficiency alpha-Tocopherol |
| Zdroj: | Experimental Biology and Medicine. 109:8-10 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-109-27085 |
| Popis: | SummaryNormal and Vit. E-deficient rabbits were injected with glycine-1-C14 and sacrificed at time intervals ranging from 0.5 to 12 hours. Homogenates of skeletal muscle were fractionated by differential centrifugation, and specific activity of the subcellular protein fractions determined. In all subcellular fractions and at all time intervals the proteins of Vit. E-deficient animals had a much higher specific activity. The effect of Vit. E-deficiency on incorporation of glycine-C14 was approximately the same in all subcellular protein fractions. Compared with control animals the radioactivity of the nonprotein supernatant fraction rose and fell faster in muscle of Vit. E-deficient animals. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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