Delayed hypersensitive reactions in bursectomized chickens

Autor: Dafina Milošević, Branislav D. Janković, Ljiljana Popesković, Milorad Išvaneski
Rok vydání: 1963
Předmět:
Zdroj: Nature. 198
ISSN: 0028-0836
Popis: IT has been recently shown that the thymus in mammals1–7 and the bursa of Fabricius in birds8–12 play a major part in maintaining the immunological integrity of the organism13. Antibody formation and delayed hypersensitive reactions in rats and mice were significantly suppressed by thymectomy performed at birth, whereas the extirpation of the bursa of Fabricius in newly hatched chickens was followed by marked reduction of their ability to produce antibodies to bacterial and protein antigens. However, tho effect of bursectomy on hypersensitivity states in birds has not been investigated. This communication deals with the hypersensitive capacity of bursectomized fowls.
Databáze: OpenAIRE