Portal vein thrombosis associated with high 14-day and 6-week rebleeding in patients after oesophageal variceal band ligation: a retrospective, multicentre, nested case-control study
| Autor: | Yanjing Gao, Xiaofeng Liu, Zhanjuan Gao, Minghui Wang, Senlin Li, Jingrun Zhao |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Liver Cirrhosis
Venous Thrombosis medicine.medical_specialty Hepatology business.industry Portal Vein Hazard ratio medicine.disease Esophageal and Gastric Varices Gastroenterology Thrombosis Confidence interval Portal vein thrombosis Internal medicine Case-Control Studies Nested case-control study medicine Humans Superior mesenteric vein Risk factor business Gastrointestinal Hemorrhage Ligation Retrospective Studies |
| Zdroj: | Hepatology international. 15(5) |
| ISSN: | 1936-0541 |
| Popis: | The association between prognosis of variceal bleeding and portal vein thrombosis (PVT) is unclear. In this multicentre study, we determined the effect of PVT on rebleeding and mortality in patients with acute variceal bleeding (AVB) after oesophageal variceal band ligation (EVL). Cirrhotic patients with AVB who had undergone EVL were included. The patients were allocated to either the PVT group or the control cirrhotic group (CCG) based on the presence or absence of PVT. One-year rebleeding episodes and mortality after EVL were recorded. A total of 218 cirrhotic patients with AVB from 3 centres were included. Patients with PVT had a higher rate of 14-day and 6-week rebleeding than those without PVT (14-day: 8.26% vs. 1.83%, p = 0.03; 6-week: 11.92% vs. 1.83%, p = 0.003). The rates of 5-day failure (3.67% vs. 0.92%, p = 0.175), 1-year rebleeding (21.10% vs. 20.18%, p = 0.867), and 14-day, 6-week, and 1-year mortality were similar between the groups (14-day: 3.67% vs. 0.92%, p = 0.175; 6-week: 3.67% vs. 0.92%, p = 0.175; 1-year: 3.67% vs. 1.83%, p = 0.408). The Child–Pugh class [p = 0.022, hazard ratio (HR): 1.453; 95% confidence interval (CI) 1.056–1.998], PVT (p = 0.050, HR: 4.622, 95% CI 0.999–21.395), albumin |
| Databáze: | OpenAIRE |
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