Xeonon accumulation in the red blood cell. A process latered by suppressors of the membrane active transport function
| Autor: | L. Ciuca, R. Chirvasie, Dragomir Ct, F. Tudor, I. Georgescu, D.T. Stefánescu, G.N. Stere, Ungureanu D |
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| Rok vydání: | 1975 |
| Předmět: |
inorganic chemicals
Erythrocytes Time Factors Xenon Cell Biophysics chemistry.chemical_element Biological Transport Active Biochemistry Ouabain medicine Humans chemistry.chemical_classification integumentary system Cell Membrane Temperature Cell Biology Metabolism Red blood cell Kinetics Membrane Enzyme medicine.anatomical_structure chemistry Dinitrophenol Potassium Calcium Mathematics circulatory and respiratory physiology medicine.drug |
| Zdroj: | Biochimica et biophysica acta. 389(3) |
| ISSN: | 0006-3002 |
| Popis: | Xenon passage across the erythrocyte membrane was investigated by performing several types of tests. The effects of some enzyme inhibitors (ouabain, NaF, dinitrophenol, low temperature), representing various modifications of the mentioned transport phenomenon, led to the conclusion of the existence of a strong correlation between the cellular energetic metabolism (and, hence, the energy supply for membrane processes) and the xenon accumulation into the erythrocyte. The experimental data obtained indicate that the xenon concentration in the cell water exceeds the concentration in the incubation solution by about 20 %. The metabolic inhibitors practically equalise the xenon concentrations in the cell water and in the surrounding medium. The possible theoretical consequences of these facts are taken into account and analysed. |
| Databáze: | OpenAIRE |
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