Consensus Statement on Research Definitions for Drug-Resistant Tuberculosis in Children
| Autor: | Seddon, JA, Perez-Velez, CM, Schaaf, HS, Furin, JJ, Marais, BJ, Tebruegge, M, Detjen, A, Hesseling, AC, Shah, S, Adams, LV, Starke, JR, Swaminathan, S, Becerra, MC, Sentinel Project on Pediatric Drug-Resistant Tuberculosis |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Pediatrics Evidence-based practice Tuberculosis Consensus Alternative medicine Disease Drug resistance Terminology Sentinel Project on Pediatric Drug-Resistant Tuberculosis Severity of illness medicine Adverse effect Children Pediatric business.industry Drug-Resistance General Medicine Definition medicine.disease Infectious Diseases Family medicine Pediatrics Perinatology and Child Health business Original Articles and Commentaries |
| Zdroj: | Journal of the Pediatric Infectious Diseases Society |
| ISSN: | 2048-7193 |
| Popis: | Few children with drug-resistant (DR) tuberculosis (TB) are identified, diagnosed, and given an appropriate treatment. The few studies that have described this vulnerable population have used inconsistent definitions. TheWorld Health Organization (WHO) definitions used for adults with DR-TB and for children with drug-susceptible TB are not always appropriate for children with DR-TB. The Sentinel Project on Pediatric Drug-Resistant Tuberculosis was formed in 2011 as a network of experts and stakeholders in childhood DRTB. An early priority was to establish standardized definitions for key parameters in order to facilitate study comparisons and the development of an evidence base to guide future clinical management. This consensus statement proposes standardized definitions to be used in research. In particular, it suggests consistent terminology, as well as definitions for measures of exposure, drug resistance testing, previous episodes and treatment, certainty of diagnosis, site and severity of disease, adverse events, and treatment outcome. © The Author 2013. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. |
| Databáze: | OpenAIRE |
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