Efficacy and tolerability of mirtazapine and sertraline in Korean veterans with posttraumatic stress disorder: A randomized open label trial
| Autor: | Sung Soo Kim, Eun Mi Jun, Wan Chul Kim, Yong Ju Jun, Moon Yong Chung, Kyung Ho Min |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Clinician Administered PTSD Scale Mirtazapine Mianserin law.invention Stress Disorders Post-Traumatic Randomized controlled trial law Sertraline Internal medicine medicine Humans Pharmacology (medical) Psychiatry Aged Veterans Korea Hamilton Rating Scale for Depression Middle Aged Psychiatry and Mental health Neurology Tolerability Clinical Global Impression Neurology (clinical) medicine.symptom Psychology Somnolence medicine.drug |
| Zdroj: | Human Psychopharmacology: Clinical and Experimental. 19:489-494 |
| ISSN: | 1099-1077 0885-6222 |
| DOI: | 10.1002/hup.615 |
| Popis: | Background The aim of this study was to investigate the potential use of mirtazapine in Korean veterans diagnosed with PTSD, by comparing it with sertraline, a drug approved for use in PTSD in the USA. Methods Efficacy was evaluated by the clinician administered PTSD scale (CAPS-2), the Hamilton rating scale for depression (HAMD-17) and the clinical global impression scale (CGI), at baseline and at weeks 1, 2 and 6. A response was defined as a ≥ 30 % decrease in CAPS-2 total severity, a ≥ 50 % decrease in total HAMD-17 score, and a CGI-I score |
| Databáze: | OpenAIRE |
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