Epstein-Barr virus infection mechanisms
| Autor: | Liudmila S. Chesnokova, Lindsey M. Hutt-Fletcher |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Cell type
Epstein-Barr Virus Infections Herpesvirus 4 Human complement receptor type 2 Cell Review Virus Physiological Phenomena Biology Virus Viral Proteins Viral entry medicine Epstein–Barr virus infection Glycoproteins chemistry.chemical_classification B-Lymphocytes Epithelial Cells medicine.disease Virology Cell biology medicine.anatomical_structure HLA class II Oncology chemistry Cytoplasm integrins entry Glycoprotein |
| Zdroj: | Chinese Journal of Cancer |
| ISSN: | 1944-446X 1000-467X |
| Popis: | Epstein-Barr virus (EBV) infection occurs by distinct mechanisms across different cell types. EBV infection of B cells in vitro minimally requires 5 viral glycoproteins and 2 cellular proteins. By contrast, infection of epithelial cells requires a minimum of 3 viral glycoproteins, which are capable of interacting with one or more of 3 different cellular proteins. The full complement of proteins involved in entry into all cell types capable of being infected in vivo is unknown. This review discusses the events that occur when the virus is delivered into the cytoplasm of a cell, the players known to be involved in these events, and the ways in which these players are thought to function. |
| Databáze: | OpenAIRE |
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