Fatal Spontaneous Tumor Lysis Syndrome in a Patient with Metastatic Colon Cancer: A Clinical Case of Rare Oncological Emergency
| Autor: | Wolfgang Josef März, Robert Fiedler, Inna Shaforostova, Johannes Pflumm, Martina Zander |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Chemotherapy
medicine.medical_specialty Colorectal cancer business.industry medicine.medical_treatment Gastroenterology Metabolic acidosis medicine.disease Tumor lysis syndrome spontaneous tumor lysis syndrome Case and Review colon cancer Internal medicine medicine Anuria lcsh:Diseases of the digestive system. Gastroenterology Renal replacement therapy medicine.symptom tumor lysis syndrome lcsh:RC799-869 business Complication Metastatic colon cancer |
| Zdroj: | Case Reports in Gastroenterology, Vol 14, Iss 2, Pp 255-260 (2020) Case Reports in Gastroenterology |
| ISSN: | 1662-0631 |
| Popis: | Tumor lysis syndrome (TLS) is a potentially life-threatening complication of chemotherapy. It usually occurs in rapidly proliferating hematological malignancies. TLS is deemed spontaneous (STLS) when it occurs prior to any cytotoxic or definite treatment. STLS is extremely rare in solid tumors. Here, we report a rare case of fatal STLS in a 47-year-old woman diagnosed with metastatic colon cancer. The patient developed acute renal failure with anuria, electrolyte disturbances, and metabolic acidosis before initiating chemotherapy. Despite appropriate management of TLS, including renal replacement therapy, she died within a few days from multiorgan failure. Only few other case reports of STLS associated with colon cancer have been reported in the literature. |
| Databáze: | OpenAIRE |
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