Repeat LEEP conization in patients with cervical intraepithelial neoplasia grade 3 and positive ectocervical margins
| Autor: | Ali Ayhan, Ibrahim Esinler, Suleyman Guven, N. Utku Dogan, F. Kubra Boynukalin, Alp Usubutun |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Reoperation medicine.medical_specialty Electrosurgery medicine.medical_treatment Conization Uterine Cervical Neoplasms Cervical intraepithelial neoplasia Young Adult Carcinoma Medicine Humans Stage (cooking) Neoplasm Staging Retrospective Studies Gynecology Cervical cancer business.industry Chronic Cervicitis Obstetrics and Gynecology General Medicine Middle Aged medicine.disease Uterine Cervical Dysplasia High Grade Cervical Intraepithelial Neoplasia Carcinoma Squamous Cell Female Neoplasm Recurrence Local business Microinvasive Squamous Cell Carcinoma Follow-Up Studies |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 105(1) |
| ISSN: | 1879-3479 |
| Popis: | Objective To evaluate the effectiveness of repeat loop electrosurgical excision procedure (LEEP) conization in patients with cervical intraepithelial neoplasia (CIN) grade 3 and positive ectocervical margins. Method A retrospective study of 56 women who underwent repeat LEEP conization for CIN 3 and positive ectocervical margins. Results Final diagnosis after repeat LEEP conization revealed 6 women (10.7%) with microinvasive squamous cell carcinoma (Stage IA1); 1 (1.8%) with CIN 1; 1 (1.8%) with CIN 2; 21 (37.5%) with CIN 3; and 27 (48.2%) with chronic cervicitis. Ectocervical or endocervical margins were negative after repeat LEEP conization in the majority of women, except for 2 patients (3.6%) with CIN 3 and positive ectocervical margins. Recurrence rate for the median follow-up time of 2 years was 6.1% (3 patients). Conclusion Repeat LEEP conization can reveal undiagnosed microinvasive cervical carcinoma in women with positive ectocervical margins. |
| Databáze: | OpenAIRE |
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