Insulin, Glucagon, and Glucose Exhibit Synchronous, Sustained Oscillations in Fasting Monkeys
Autor: | Arthur C. Brown, Jerry P. Palmer, Lynne W. Kalnasy, Barbara C. Walike, Charles J. Goodner, Donna J. Koerker, Elliott W. Chideckel, John W. Ensinck |
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Rok vydání: | 1977 |
Předmět: |
Atropine
Blood Glucose Periodicity endocrine system medicine.medical_specialty Pulsatile insulin Period (gene) medicine.medical_treatment Biology Glucagon Eating Islets of Langerhans Internal medicine medicine Animals Insulin Sustained oscillations Multidisciplinary Insulin blood Fasting Haplorhini Macaca mulatta Out of phase Endocrinology Liver Plasma concentration hormones hormone substitutes and hormone antagonists |
Zdroj: | Science. 195:177-179 |
ISSN: | 1095-9203 0036-8075 |
Popis: | In overnight fasted rhesus monkeys, synchronous, regular oscillations occurred in the plasma concentrations of glucose, insulin, and glucagon. The oscillations displayed a period averaging 9 minutes. The amplitudes for insulin and glucagon were ten and five times greater than for glucose. Insulin cycled in and glucagon out of phase with glucose. In baboons, oscillations of glucose and insulin were smaller than in rhesus monkeys, while in man, regular oscillations were not observed. |
Databáze: | OpenAIRE |
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