Evaluation of role of concentration and molecular weight of oat β-glucan in determining effect of viscosity on plasma glucose and insulin following an oral glucose load
| Autor: | Peter J. Wood, G. Butler, M. U. Beer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Glucose tolerance test Nutrition and Dietetics Chromatography Logarithm medicine.diagnostic_test Chemistry Insulin medicine.medical_treatment Size-exclusion chromatography Medicine (miscellaneous) Viscometer Blood sugar Endocrinology Postprandial Internal medicine medicine sense organs Glucan |
| Popis: | Data from clinical studies established that there was an inverse linear relationship between measures of postprandial blood glucose and insulin responses to an oral glucose load, consumed in a drink, and the logarithm of viscosity of the drink. These data have been re-analysed using concentration and molecular weight as the dependent variables. Molecular weight (M) of the β-glucans used was determined using high-performance size exclusion chromatography equipped with a triple detector system of right angle light scattering, viscometry and refractive index. A significant relationship between changes in peak blood glucose and a combination of logarithm of the concentration and logarithm of M was found. |
| Databáze: | OpenAIRE |
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