Skin autofluorescence as tool for cardiovascular and diabetes risk prediction
| Autor: | Andries Jan, Smit, Saskia Corine, van de Zande, Douwe Johannes, Mulder |
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| Rok vydání: | 2022 |
| Předmět: |
Glycation End Products
Advanced end-stage renal disease DISEASE receptor for advanced glycation endproducts skin autofluorescence Diabetes Mellitus Type 2 Cardiovascular Diseases Nephrology SCORE Internal Medicine Humans COHORT Renal Insufficiency advanced glycation endproducts chronic kidney disease Skin |
| Zdroj: | Current Opinion in Nephrology & Hypertension. 31:522-526 |
| ISSN: | 1473-6543 1062-4821 |
| DOI: | 10.1097/mnh.0000000000000835 |
| Popis: | Purpose of review Advanced glycation endproducts (AGE) have an important role in the development of chronic complications in diabetes mellitus and in renal failure. Skin autofluorescence (SAF) is a simple noninvasive optical technique to estimate AGE levels in the dermis. SAF increases with age, but rises more rapidly in diabetes and renal failure, and is also associated with, and a predictor of their complications. Recent findings In recent large population studies, SAF is a strong predictor of development of type 2 diabetes (T2D), and in persons with known diabetes of its complications. SAF also predicts new cardiovascular disease (CVD) and mortality not only in individuals with known type 2 diabetes but also in the general population. SAF is a simple, powerful and independent predictor for development of type 2 diabetes (T2D), and also for cardiovascular disease and mortality in both persons with diabetes, and in the general population. |
| Databáze: | OpenAIRE |
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