Renaissance of traditional DNA transfer strategies for improvement of industrial lactic acid bacteria
| Autor: | Michiel Kleerebezem, Luiza P. Morawska, Joyce Mulder, Oscar P. Kuipers, Barbara Marcelli, Peter A. Bron, Jan Kok, Simon van der Els |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Gene Transfer Horizontal DEFENSE competence Biomedical Engineering Bioengineering Genomics Computational biology 01 natural sciences 03 medical and health sciences Transduction (genetics) Plasmid Genome editing Lactobacillales Transduction Genetic 010608 biotechnology ELEMENTS genome editing TOOL CRISPR Life Science Clustered Regularly Interspaced Short Palindromic Repeats Host-Microbe Interactomics CRISPR-CAS 030304 developmental biology VLAG Gene Editing 0303 health sciences NATURAL COMPETENCE biology Natural competence biology.organism_classification TRANSFORMATION EVOLUTION lactic acid bacteria Horizontal gene transfer Food Microbiology WIAS BIODIVERSITY CRISPR-Cas Systems CRISPR-Cas9 GENOMICS PLASMID Bacteria Biotechnology |
| Zdroj: | Current Opinion in Biotechnology 56 (2019) Current Opinion in Biotechnology, 56, 61-68 |
| ISSN: | 0958-1669 |
| Popis: | The ever-expanding genomic insight in natural diversity of lactic acid bacteria (LAB) has revived the industrial interest in traditional and natural genetic mobilization methodologies. Here, we review recent advances in horizontal gene transfer processes in LAB, including natural competence, conjugation, and phage transduction. In addition, we envision the possibilities for industrial strain improvement arising from the recent discoveries of molecular exchanges between bacteria through nanotubes and extracellular vesicles, as well as the constantly expanding genome editing possibilities using the CRISPR-Cas technology. |
| Databáze: | OpenAIRE |
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