Anticonvulsant activity of Mimosa pudica decoction

Autor:	D.L Dawack, E. Ngo Bum, A Rakotonirina, S.V Rakotonirina, A. Jeker, Markus Schmutz, P Herrling, H. R. Olpe, C. Portet
Rok vydání:	2004
Předmět:	Male Mimosa medicine.medical_treatment Decoction Pharmacognosy law.invention Mice chemistry.chemical_compound Seizures law Drug Discovery Animals Medicine Medicine African Traditional Pharmacology Folk medicine Dose-Response Relationship Drug Traditional medicine biology Plant Extracts business.industry Mimosa pudica Strychnine General Medicine biology.organism_classification Plant Leaves Anticonvulsant chemistry Pentylenetetrazole Anticonvulsants African traditional medicine business Phytotherapy Injections Intraperitoneal
Zdroj:	Fitoterapia. 75:309-314
ISSN:	0367-326X
Popis:	The decoction of Mimosa pudica leaves given intraperitoneally at dose of 1000-4000 mg/kg protected mice against pentylentetrazol and strychnine-induced seizures. M. pudica had no effect against picrotoxin-induced seizures It also antagonized N-methyl-D-aspartate- induced turning behavior. These properties could explain its use in African traditional medicine.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69618845f47dc002c3625684566376ff https://doi.org/10.1016/j.fitote.2004.01.012 Zobrazit plný text záznamu Full Text from ScienceDirect