Comparison of corifollitropin alfa and daily recombinant follicle-stimulating hormone in poor responder patients undergoing in vitro fertilization cycles
| Autor: | Funda Gode, Ahmet Zeki Işık, Süleyman Akarsu, Sibel Demir |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Infertility
medicine.drug_class medicine.medical_treatment Corifollitropin alfa lcsh:Medicine Controlled ovarian hyperstimulation lcsh:Gynecology and obstetrics Gonadotropin-releasing hormone antagonist Andrology Human fertilization Medicine Clinical Investigation lcsh:RG1-991 gonadotropin-releasing hormone antagonist In vitro fertilisation business.industry lcsh:R Obstetrics and Gynecology poor responder Antral follicle medicine.disease Oocyte Sperm medicine.anatomical_structure business in vitro fertilization diminished ovarian reserve |
| Zdroj: | Turkish Journal of Obstetrics and Gynecology Turkish Journal of Obstetrics and Gynecology, Vol 14, Iss 4, Pp 199-202 (2017) |
| ISSN: | 2149-9330 1307-699X |
| DOI: | 10.4274/tjod.08634 |
| Popis: | Objective: The aim of this study was to compare the effect of corifollitropin alfa (CFA) and recombinant follicle-stimulating hormone (rFSH) in poor-responder patients undergoing antagonist cycles. Materials and Methods: The study was a retrospective analysis of the treatment results of 214 poor responder patients who had been admitted to the In Vitro Fertilization Unit of İzmir Medical Park Hospital between November 2014 and November 2016. Intracytoplasmic sperm injections were performed in 38 patients (group 1) with CFA, and the remaining 176 (group 2) with rFSH for controlled ovarian hyperstimulation. Results: The age, body mass index, anti-müllerian hormone level, duration of infertility, duration of induction and antral follicle number were similar in the two groups. There was no difference in the total aspirated oocyte counts, mature oocyte ratio, fertilization rate, implantation rate, and clinical pregnancy rates between the two groups. The implantation rate was 9/38 (23.6%) in group 1 and 42/176 (23.8%) in group 2, whereas the clinical pregnancy rates were 16.3% and 17.2%, respectively. Conclusion: No difference was found in terms of oocyte count, fertilization rate, implantation rate, and clinical pregnancy rates of CFA or rFSH use in the antagonist cycles in poor-responder patients. © 2017 by Turkish Society of Obstetrics and Gynecology. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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