Blood Pressure Changes in Adolescents with Preeclampsia: A Multicentre, Case-Control Study in Latin American Hospitals
| Autor: | Carlos Mata Hernández, Jorge Cerrato-Ferrufino, Paulino Vigil-De Gracia, Osvaldo Reyes-Tejada, Sandra Ximena Olaya-Garay, Patricia Asturizaga-Soto, Santiago Cabrera, Jorge Arturo Collantes-Cubas |
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| Rok vydání: | 2021 |
| Předmět: |
Gestational hypertension
medicine.medical_specialty Adolescent Diastole Blood Pressure Sensitivity and Specificity Likelihood ratios in diagnostic testing Preeclampsia Young Adult Pre-Eclampsia Predictive Value of Tests Pregnancy Internal medicine medicine Humans Eclampsia business.industry Area under the curve Obstetrics and Gynecology Blood Pressure Monitoring Ambulatory medicine.disease Hospitals Latin America Minimum blood pressure Blood pressure Case-Control Studies Hypertension Pregnancy in Adolescence Cardiology Female business |
| Zdroj: | Journal of Obstetrics and Gynaecology Canada. 43:50-57 |
| ISSN: | 1701-2163 |
| DOI: | 10.1016/j.jogc.2020.06.024 |
| Popis: | Objective To determine the minimum blood pressure increases that would confirm or exclude, with the greatest predictive values, hypertensive disorders of pregnancy (HDP) in pregnant adolescents after 24 weeks gestation. Methods We conducted a case-control study of pregnant women aged ≤19 years with and without HDP. Using systolic and diastolic blood pressure increases, a predictive analysis was performed, and the area under the curve was calculated. Results The cases and controls had systolic blood pressure increases of 45.3 ± 17.5 mm Hg and 6.4 ± 7.9 mm Hg, respectively (P = 0.001) and diastolic blood pressure increases of 30.8 ± 11.7 mm Hg and 3.5 ± 5.7 mm Hg, respectively (P = 0.001). Systolic and diastolic increases of ≥20 mm Hg showed the greatest sensitivity and specificity. A combined analysis showed that an increase of ≥20 mm Hg had a greater positive likelihood ratio of 35.4 (95% CI 22.4–55.9) and negative likelihood ratio of 0.10 (95% CI 0.07–0.13), with an area under the curve of 0.98 (95% CI 0.96–0.99). Conclusions Systolic and diastolic blood pressure increases of ≥20 mm Hg must be considered in the diagnostic criteria for preeclampsia and gestational hypertension among pregnant adolescents past 24 weeks gestation. |
| Databáze: | OpenAIRE |
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