Popis: |
A. Scatterplots and correlations between N-glycans of interest (1339, 1257, 2158) and clinical information available (ALT, AST, ALK, and AFP). B. Multivariate model-Multiple logistic regression in CCA and PSC serum samples (n=40). Model 1: three N-glycans of interest and clinical information available (left panel). Model 2: Only the three N-glycans of interest (right panel). C. ROC curve of the combination of glycans and clinical information (red-solid line) and only glycans (green-dashed line) (left), classification performance table of the two models in B. p=0.5731, Delong’s test between model 1 and 2. CA19-9, ALT, AST, ALK, and AFP values were log-transformed for plotting and modeling convenience. logALT was removed from the multiple logistic regression analysis due to a high value of Variance inflation factor (VIF). |