Insulin Delivery and Glucose Variability Throughout the Menstrual Cycle on Closed Loop Control for Women with Type 1 Diabetes

Autor:	Carol J, Levy, Grenye, O'Malley, Dan, Raghinaru, Yogish C, Kudva, Lori M, Laffel, Jordan E, Pinsker, John W, Lum, Sue A, Brown, Thomas, Eggerman
Rok vydání:	2022
Předmět:	Blood Glucose Blood Glucose Self-Monitoring Endocrinology Diabetes and Metabolism Medical Laboratory Technology Diabetes Mellitus Type 1 Glucose Insulin Infusion Systems Endocrinology Insulin Regular Human Humans Hypoglycemic Agents Insulin Female Brief Reports Menstrual Cycle
Zdroj:	Diabetes Technol Ther
ISSN:	1557-8593 1520-9156
Popis:	OBJECTIVE: To analyze insulin delivery and glycemic metrics throughout the menstrual cycle for women with type 1 diabetes using closed loop control (CLC) insulin delivery. METHODS: Menstruating women using a CLC system in a clinical trial were invited to record their menstrual cycles through a cycle-tracking application. Sixteen participants provided data for this secondary analysis over three or more complete cycles. Insulin delivery and continuous glucose monitoring (CGM) data were analyzed in relation to reported cycle phases. RESULTS: Insulin delivery and CGM metrics remained consistent during cycle phases. Intraparticipant variability of CGM metrics and weight-based insulin delivery did not change through cycle phases. CONCLUSIONS: For this sample of menstruating women with type 1 diabetes using a CLC system, insulin delivery and glycemic metrics remained stable throughout menstrual cycle phases. Additional studies in this population are needed, particularly among women who report variable glycemic control during their cycles. TRIAL REGISTRATION: NCT03591354.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6952e79447074d0eac7df954c3fafa0d https://doi.org/10.1089/dia.2021.0431 Zobrazit plný text záznamu