New development on hysteroscopy for endometrial cancer diagnosis: state of the art
| Autor: | Sergio Haimovich, Luis Alonso, Staci J. Marbin, Antonio Simone Laganà, Attilio Di Spiezio Sardo, Jose Carugno, Salvatore Giovanni Vitale |
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| Přispěvatelé: | Carugno, Jose, Marbin, Staci J, Laganà, Antonio S, Vitale, Salvatore G, Alonso, Lui, DI Spiezio Sardo, Attilio, Haimovich, Sergio |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Population Hysteroscopy 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Biopsy Humans Medicine Endometrial Neoplasm Neoplasm Metastasis education education.field_of_study medicine.diagnostic_test business.industry Risk Factor Endometrial cancer General Medicine medicine.disease Lynch syndrome Endometrial Neoplasms Neoplasm Metastasi 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology business Ovarian cancer Tamoxifen Human Endometrial biopsy medicine.drug |
| Popis: | Endometrial cancer (EC) is the most common gynecologic cancer diagnosed in developed countries and represents the second most frequent gynecologic cancer-related cause of death following ovarian cancer. There are 2 subtypes of EC. Type I tumors (endometrioid adenocarcinoma) representing 85-90% of the cases. They are likely to be low-grade tumors and are thought to have a link to estrogen exposure. Type II tumors represent 10-15% of EC. They are characterized as high-grade carcinomas, with serous or clear cell histology type, and carry poor prognoses. The benefits of hysteroscopy in achieving a targeted endometrial biopsy under direct visualization over blind biopsy techniques are widely accepted. Hysteroscopic endometrial biopsy is performed under direct visualization and is the only technique that allows for the selective biopsy of targeted areas of the endometrium. There is no screening protocol for the early detection of EC. Among the general population, advanced age, obesity, nulliparity and the use of exogenous hormones are known as risk factors for EC. There are additional situations that portend an increased risk of EC that deserve special consideration such as in patients diagnosed with Lynch Syndrome, using tamoxifen, obese, or the young patient with a desire for future fertility. We presented a narrative review of the current role of hysteroscopy for the diagnosis of endometrial cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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