P Wave Peak Time for Predicting an Increased Left Atrial Volume Index in Hemodialysis Patients
| Autor: | İbrahim Rencüzoğulları, İbrahim Yıldız, Pinar Ozmen Yildiz, Yavuz Karabağ, Guner Karaveli Gursoy, Metin Çağdaş, Bülent Kaya, Cengiz Burak |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Heart Diseases 020205 medical informatics medicine.medical_treatment Comorbidity 02 engineering and technology Electrocardiography 03 medical and health sciences Predictive Value of Tests Renal Dialysis Internal medicine 0202 electrical engineering electronic engineering information engineering Humans Medicine Cutoff Renal Insufficiency Lead (electronics) Aged Original Paper medicine.diagnostic_test business.industry P wave Area under the curve General Medicine Odds ratio Middle Aged ROC Curve Socioeconomic Factors Cardiology Population study Atrial Function Left Female 030101 anatomy & morphology Hemodialysis business |
| Zdroj: | Med Princ Pract |
| ISSN: | 1423-0151 1011-7571 |
| DOI: | 10.1159/000503709 |
| Popis: | Objective: An increased left atrial volume index (LAVI) is related to increased mortality in hemodialysis patients. In the present study, we evaluated the association between the LAVI and the P wave peak time (PWPT), a newly introduced electrocardiographic parameter, in hemodialysis patients. Methods: The study population was made up of 79 hemodialysis patients with a mean age of 53 ± 18 years (55.7% were males). These patients were divided into a normal LAVI (≤28 mL/m2) group (n = 45) and an increased LAVI (>28 mL/m2) group (n = 34). The demographic, clinical, laboratory, echocardiographic, and electrocardiographic variables of the groups were compared. Results: The P wave terminal force from lead V1, P wave dispersion and PWPTs obtained from leads V1 and D2 (PWPTD2) were significantly higher in the patients with increased LAVIs. In multivariable analysis, only the PWPTD2was an independent predictor of an increased LAVI (odds ratio = 1.117, 95% CI = 1.052–1.185, p < 0.001). The receiver-operating characteristic curve analysis showed that the best PWPTD2 cutoff value for predicting an increased LAVI was 60 ms, with a sensitivity of 76.5% and a specificity of 66.7% (area under the curve = 0.736, 95% CI = 0.625–0.829, p < 0.001). Conclusion: This study showed that a prolonged PWPTD2 was independently associated with an increased LAVI in hemodialysis patients. Therefore, measuring the PWPTD2 duration on an electrocardiogram may help define high-risk hemodialysis patients with increased LAVIs. |
| Databáze: | OpenAIRE |
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