Microablative fractional CO 2 -laser therapy and the genitourinary syndrome of menopause: An observational study
| Autor: | Stavros Athanasiou, Stefano Salvatore, Angeliki Tsiveleka, Eleni Pitsouni, Dimitris Zacharakis, Themos Grigoriadis |
|---|---|
| Přispěvatelé: | Pitsouni, E, Grigoriadis, T, Tsiveleka, A, Zacharakis, D, Salvatore, Stefano, Athanasiou, S. |
| Rok vydání: | 2016 |
| Předmět: |
Gynecology
medicine.medical_specialty Stress incontinence 030219 obstetrics & reproductive medicine business.industry Genitourinary system Urinary system Obstetrics and Gynecology Urinary incontinence medicine.disease General Biochemistry Genetics and Molecular Biology Menopause 03 medical and health sciences Distress 0302 clinical medicine 030220 oncology & carcinogenesis Internal medicine Medicine Dysuria medicine.symptom business Sexual function |
| Zdroj: | Maturitas. 94:131-136 |
| ISSN: | 0378-5122 |
| DOI: | 10.1016/j.maturitas.2016.09.012 |
| Popis: | Objectives This study aimed to assess the effect of the Microablative Fractional CO2 Laser (CO2-laser) therapy on vaginal pathophysiology and the symptoms of the Genitourinary Syndrome of Menopause (GSM). Methods Postmenopausal women with moderate to severe symptoms of GSM underwent three sessions of CO2-laser therapy at monthly intervals. Participants were evaluated at baseline and 4 weeks after the last treatment. Main outcome measures The primary outcomes were Vaginal Maturation Value (VMV) and Vaginal Health Index Score (VHIS). Secondary outcomes included symptoms of GSM, Female Sexual Function Index (FSFI), International Consultation on Incontinence Questionnaire of Female Urinary Tract Symptoms (ICIQ-FLUTS) and Urinary Incontinence Short Form (ICIQ-UI SF), Urogenital Distress Inventory (UDI-6) and King’s Health Questionnaire (KHQ). Results Fifty-three postmenopausal women completed this study. VMV, VHIS and FSFI increased significantly. Dyspareunia, dryness, burning, itching, dysuria, frequency, urgency, urgency incontinence, stress incontinence and scores on the ICIQ-FLUTS, ICIQ-UI SF, UDI-6 and KHQ decreased significantly. Factors predicting for which women the CO2-laser therapy was more effective were not identified. Conclusion This study suggests that intravaginal CO2-laser therapy for postmenopausal women with clinical signs and symptoms of GSM may be effective in improving both vaginal pathophysiology and reported symptoms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect