Novel G-protein-coupled receptor gene expressed specifically in the entire neural tube of the ascidian Ciona intestinalis
| Autor: | Takahito Nishikata, Kazuma Etani |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
animal structures
Molecular Sequence Data Receptors Cell Surface Biology G Protein-Coupled Receptor Gene Genetics Animals Ciona intestinalis Amino Acid Sequence Cloning Molecular Receptor Gene Peptide sequence In Situ Hybridization Sequence Homology Amino Acid Gene Expression Regulation Developmental Gastrula biology.organism_classification Molecular biology Receptors Adrenergic Cell biology Transmembrane domain Neurulation Neurula embryonic structures Developmental Biology |
| Zdroj: | Development Genes and Evolution. 212:447-451 |
| ISSN: | 1432-041X 0949-944X |
| DOI: | 10.1007/s00427-002-0260-1 |
| Popis: | We have cloned a newly identified gene, designated CiNut, C iona i ntestinalis neural-tube-specific gene. CiNut shows weak similarity to known neural receptors such as adrenergic receptors. Moreover, seven transmembrane domains are predicted based on its amino acid sequence. Zygotic expression of CiNut starts at the gastrula stage, and is restricted to the entire neural tube in the neurula- and the tailbud-stage embryos. CiNut is thus thought to be a novel G-protein-coupled receptor important for neural tube formation, and should provide a useful tool for the analysis of the molecular mechanism of neural tube formation. |
| Databáze: | OpenAIRE |
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