Iron( III ) Chelation: Tuning of the pH Dependence by Mixed Ligands
| Autor: | Frédéric Biaso, Fabrice Thomas, Sylvie Blanc, Anne-Marie Albrecht-Gary, Jean-Louis Pierre, Paul Baret, Gisèle Gellon, Guy Serratrice |
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| Přispěvatelé: | Institut des sciences analytiques et de physico-chimie pour l'environnement et les materiaux (IPREM), Université de Pau et des Pays de l'Adour (UPPA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'études dynamiques et structurales de la sélectivité (LEDSS), Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2003 |
| Předmět: |
siderophore
Potentiometric titration Inorganic chemistry ultraviolet spectroscopy 010402 general chemistry proton nuclear magnetic resonance 01 natural sciences Coordination complex Inorganic Chemistry thermodynamics chemistry.chemical_compound iron 8 quinolinol complex formation Amide Polymer chemistry [CHIM]Chemical Sciences Chelation chemistry.chemical_classification iron chelation Catechol Aqueous solution 010405 organic chemistry pH measurement titrimetry 0104 chemical sciences chemistry Proton NMR Titration |
| Zdroj: | European Journal of Inorganic Chemistry European Journal of Inorganic Chemistry, Wiley-VCH Verlag, 2003, pp.2596-2605. ⟨10.1002/ejic.200200643⟩ |
| ISSN: | 1099-0682 1434-1948 |
| DOI: | 10.1002/ejic.200200643 |
| Popis: | The iron(III) chelating properties of two heteropodands with 8-hydroxyquinoline and catechol binding groups were examined and compared to those of the corresponding homopodal analogues, O-TRENSOX and TRENCAMS. Like the parent homopodands, the two heteropodands are based on the TREN scaffold and the chelating units are connected by amide groups, TRENSOX2CAMS having two 8-hydroxyquinoline and one catechol arms and TRENSOXCAMS2 one 8-hydroxyquinoline and two catechol moieties. The aqueous coordination chemistry of these ligands was examined by potentiometric and spectrophotometric methods in combination with 1H NMR spectroscopy. The respective pFeIII values showed a cooperative effect of the mixed chelating units. Moreover, the pFeIII dependence on pH showed that the mixed ligands exhibit a higher complexing ability than the parent ligands over the pH range 5−9 which is of biological relevance. This result could be of great interest for medical applications. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003) |
| Databáze: | OpenAIRE |
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