A Streptococcus pyogenes outbreak caused by an unusual serotype of low virulence: the value of typing techniques in outbreak investigations
| Autor: | Fennechien Biainczijk, Wijnanda J. van Leeuwen, B.I. Davies, J. Hirsch, H. M. J. Toenbreker, T.J. Werink |
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| Rok vydání: | 1999 |
| Předmět: |
Microbiology (medical)
Serotype Adult medicine.medical_specialty Streptococcus pyogenes Virulence medicine.disease_cause Hospitals General Polymerase Chain Reaction Microbiology Disease Outbreaks Streptococcal Infections Epidemiology Medicine Humans Surgical Wound Infection Typing Serotyping Aged Netherlands Aged 80 and over business.industry Streptococcus Outbreak Middle Aged Virology Infectious Diseases business Exotoxin |
| Zdroj: | The Journal of infection. 38(3) |
| ISSN: | 0163-4453 |
| Popis: | Objectives : to investigate and stop the spread of an outbreak of Streptococcus pgogenes infection in a district general hospital, involving 19 patients and two nurses over a 20-day period. Methods : all suspected persons were investigated using conventional bacteriological techniques, followed by M, T and exotoxin gene-typing of the isolates in a national reference laboratory. Results : 11 patients and both nurses were associated with the acute surgical ward on one floor of the hospital. They were infected with serotype M 9/T 133264, a strain with apparently low virulence, which has not been previously associated with outbreaks. Two other patients on the same floor each had different types and there were two clusters of another S. pgogenes serotype on other floors, each involving two patients. Two (unrelated) patients yielded other types of S. pgogenes . The patients were not seriously ill but had some delay in wound healing. Conclusions : the value of typing the isolates of S. Pyogenes in this outbreak was in defining which patients were involved. No added value could be ascribed to the exotoxin gene-typing results. |
| Databáze: | OpenAIRE |
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