Near-patient test for nicotine and its metabolites in saliva to assess smoking habit
| Autor: | Gareth R. Brock, Pamela Nayyar, Roger Holder, Graham Cope, Iain L. C. Chapple |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Saliva medicine.medical_specialty Nicotine Metabolite Point-of-Care Systems Clinical Biochemistry Statistics as Topic Radioimmunoassay Physiology Sensitivity and Specificity Colorimetry (chemical method) chemistry.chemical_compound Saliva testing Medicine Humans Cotinine business.industry Colorimeter Smoking General Medicine Surgery chemistry Colorimetry Female Smoking Cessation business medicine.drug |
| Zdroj: | Annals of clinical biochemistry. 37 |
| ISSN: | 0004-5632 |
| Popis: | Smoking is a major risk factor for periodontal disease, causing bone and tooth loss. Effective management of many oral conditions requires accurate information about smoking. We describe a disposable, 10-min, near-patient saliva test to monitor cigarette smoking. A plastic device contains the dried reagents to measure nicotine and its metabolites by a colorimetric assay. The device can be used to give a semi-quantitative assessment of tobacco consumption by observing a colour change and comparing it to a reference chart. Alternatively, the test can be quantified by measuring the light absorbance with a colorimeter and determining the concentration of nicotine metabolites by reference to a cotinine standard. This method correlates with reported daily cigarette consumption ( r=0·62, P< 0·0001) and nicotine yield of cigarettes smoked ( r=0·35, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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