Elevated blood pressure level based on 2017 ACC/AHA guideline in relation to stroke risk in rural areas of Liaoning province
| Autor: | Liqiang Zheng, Zhaoqing Sun, Guozhe Sun, Zhao Li, Yanxia Xie, Jia Zheng, Xiaofan Guo, Yingxian Sun, Mingfeng Ma |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male China lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty Time Factors Rural Health 030204 cardiovascular system & hematology Risk Assessment Prehypertension 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Prevalence medicine Humans cardiovascular diseases 030212 general & internal medicine Prospective study Rural area Prospective cohort study Stroke business.industry Incidence Incidence (epidemiology) Hazard ratio Guideline Middle Aged Prognosis medicine.disease Confidence interval Blood pressure lcsh:RC666-701 Hypertension Cardiology Female Cardiology and Cardiovascular Medicine business Research Article |
| Zdroj: | BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-8 (2019) BMC Cardiovascular Disorders |
| ISSN: | 1471-2261 |
| Popis: | Background The new ACC/AHA hypertension guideline lower the definition of hypertension from 140/90 mmHg to 130/80 mmHg and eliminate the category of prehypertension thus increasing the prevalence of hypertension. A purpose of this study is to explore the applicability of the new guidelines in rural China. Methods In total, 3229 participants aged ≥35 years and free of stroke at baseline were followed for up to 4.8 years during 2012 to 2017 in a rural community-based prospective cohort study of Xifeng County. The hazard ratio (HR) and 95% Confidence interval (CI) of different blood pressure (BP) levels for risk of incident stroke were analyzed by multivariable Cox proportional hazard models. Results During the follow-up, 81 new strokes occurred among the 3229 participants. Compared with normal BP (Systolic BP (SBP)P = 0.020). However, there was no significant association between elevated (SBP:120-129 mmHg and DBPP = 0.888; HR: 0.96, 95% CI: 0.46 to 2.02, P = 0.920, respectively). An increase of the SBP by 1-SD increases the risk for stroke by 56% (HR: 1.56, 95%CI: 1.29 to 1.88, P P Conclusions Compared with normal BP, the stage 2 hypertension based on 2017 ACC/AHA guideline significantly increases the risk of stroke incidence, but this association was not observed between elevated, stage1 hypertension and stroke incidence in Chinese rural adults. |
| Databáze: | OpenAIRE |
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