Delayed Total Knee Replacement with Hylan G-F 20
| Autor: | David D Waddell, Biji Joseph |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male musculoskeletal diseases medicine.medical_specialty Time Factors Knee Joint medicine.medical_treatment Total knee replacement Osteoarthritis Injections Intra-Articular Humans Medicine Orthopedics and Sports Medicine Hyaluronic Acid Arthroplasty Replacement Knee Survival analysis Aged Retrospective Studies Aged 80 and over Viscosupplements business.industry Incidence (epidemiology) Retrospective cohort study Middle Aged Osteoarthritis Knee medicine.disease Arthroplasty humanities Surgery Orthopedic surgery Cohort Female business |
| Zdroj: | Journal of Knee Surgery. 29:159-168 |
| ISSN: | 1938-2480 1538-8506 |
| DOI: | 10.1055/s-0034-1395281 |
| Popis: | We retrospectively examined prospective data on the incidence and time to total knee replacement (TKR) in (1) patients with grade IV osteoarthritis (OA) treated with hylan G-F 20 from 1997 to 2010 (full cohort; 1,863 knees) and (2) a patient subset treated from 1997 to 2003 (original cohort; 1,187 knees) to determine any continued hylan G-F 20 influence on TKR delay. In both the cohorts, 25 to 28% knees underwent a TKR, with an average of 2.8 to 3.1 years occurring between hylan G-F 20 and surgery. Age was a significant predictor of time to TKR. Knee synovitis increased slightly with repeat courses; most cases considered mild or moderate. Survival analysis showed that TKR was delayed for > 7 years in 75% of 1,863 grade IV OA knees (1,342 patients) treated with hylan G-F 20 in an orthopedic practice. Consistent with our previous report (Waddell and Bricker, 2007), we show hylan G-F 20 continues to delay the need for TKR. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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