When polymers meet carbon nanostructures: expanding horizons in cancer therapy
Autor: | Francesca Iemma, Giuseppe Cirillo, Manuela Curcio, Anna Dubrovska, Florida Voli, Silke Hampel, Orazio Vittorio, Maria Kavallaris, Annafranca Farfalla, Claudia Peitzsch |
---|---|
Rok vydání: | 2019 |
Předmět: |
Materials science
Polymers Cancer therapy Oxide chemistry.chemical_element Nanotechnology 02 engineering and technology Carbon nanotube 010402 general chemistry 01 natural sciences law.invention chemistry.chemical_compound law Neoplasms Drug Discovery Animals Humans Pharmacology chemistry.chemical_classification Nanotubes Carbon Polymer 021001 nanoscience & nanotechnology Carbon Nanostructures 0104 chemical sciences Nanomedicine chemistry Drug delivery Molecular Medicine Functional polymers 0210 nano-technology Hybrid material |
Zdroj: | Future Medicinal Chemistry. 11:2205-2231 |
ISSN: | 1756-8927 1756-8919 |
Popis: | The development of hybrid materials, which combine inorganic with organic materials, is receiving increasing attention by researchers. As a consequence of carbon nanostructures high chemical versatility, they exhibit enormous potential for new highly engineered multifunctional nanotherapeutic agents for cancer therapy. Whereas many groups are working on drug delivery systems for chemotherapy, the use of carbon nanohybrids for radiotherapy is rarely applied. Thus, nanotechnology offers a wide range of solutions to overcome the current obstacles of conventional chemo- and/or radiotherapies. Within this review, the structure and properties of carbon nanostructures (carbon nanotubes, nanographene oxide) functionalized preferentially with different types of polymers (synthetic, natural) are discussed. In short, synthesis approaches, toxicity investigations and anticancer efficacy of different carbon nanohybrids are described. |
Databáze: | OpenAIRE |
Externí odkaz: |