Development of the alopecia areata scale for clinical use: Results of an academic–industry collaborative effort
| Autor: | Crystal Aguh, Eric Ghorayeb, Justine Koenigsberg, Steven Fakharzadeh, Natasha Atanaskova Mesinkovska, Lynne Napatalung, Justin M. Ko, Amy J. McMichael, Amy S. Paller, Fabio P. Nunes, Carolyn Goh, Paradi Mirmirani, Melissa Piliang, Amy M. DeLozier, Maryanne M. Senna, Kristen Lo Sicco, Chesahna Kindred, Pedram Yazdan, Antonella Tosti, Wilma F. Bergfeld, Maria K. Hordinsky, Brittany G. Craiglow, Kavita Gandhi, Marc Glashofer, Jerry Shapiro, Leslie Castelo-Soccio, Kathie P. Huang, Gurpreet Ahluwalia, Brett A. King, James V. Cassella, Julian Mackay-Wiggan |
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| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
Consensus Alopecia Areata business.industry Modified delphi Alopecia macromolecular substances Dermatology Alopecia areata medicine.disease Severity of Illness Index Clinical Practice Clinical trial Scale (social sciences) Family medicine medicine Severity Criteria Humans In patient business Pharmaceutical industry |
| Zdroj: | Journal of the American Academy of Dermatology. 86:359-364 |
| ISSN: | 0190-9622 |
| Popis: | Background The current classification for alopecia areata (AA) does not provide a consistent assessment of disease severity. Objective To develop an AA severity scale based on expert experience. Methods A modified Delphi process was utilized. An advisory group of 22 AA clinical experts from the United States was formed to develop this AA scale. Representatives from the pharmaceutical industry provided feedback during its development. Results Survey responses were used to draft severity criteria, aspiring to develop a simple scale that may be easily applied in clinical practice. A consensus vote was held to determine the final AA severity statement, with all AA experts agreeing to adopt the proposed scale. Limitations The scale is a static assessment intended to be used in clinical practice and not clinical trials. Conclusion The final AA disease severity scale, anchored in the extent of hair loss, captures key features commonly used by AA experts in clinical practice. This scale will better aid clinicians in appropriately assessing severity in patients with this common disease. |
| Databáze: | OpenAIRE |
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