Distribution of grafted β-cyclodextrin in porous particles for bone tissue engineering
| Autor: | Maria V. Juhl, Jeppe Lund Nielsen, Naseem Theilgaard, Kim Lambertsen Larsen, Peter Andreas Lund Jacobsen, Jens Rafaelsen |
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| Rok vydání: | 2013 |
| Předmět: |
chemistry.chemical_classification
Materials science Cyclodextrin Silica gel Analytical chemistry General Chemistry Condensed Matter Physics Grafting Focused ion beam law.invention chemistry.chemical_compound chemistry Mechanics of Materials law General Materials Science Electron microscope Porosity Porous medium Penetration depth |
| Zdroj: | Jacobsen, P A L, Rafaelsen, J, Nielsen, J L, Juhl, M V, Theilgaard, N & Larsen, K L 2013, ' Distribution of grafted β-cyclodextrin in porous particles for bone tissue engineering ', Microporous and Mesoporous Materials, vol. 168, pp. 132-141 . https://doi.org/10.1016/j.micromeso.2012.10.001 |
| ISSN: | 1387-1811 |
| DOI: | 10.1016/j.micromeso.2012.10.001 |
| Popis: | The spatial distribution of β-cyclodextrin grafted to a range of porous materials was investigated. (3-glycidyloxypropyl)trimethoxysilane was used to facilitate the covalent grafting of β-cyclodextrin. The spatial distribution was analysed by combining results from confocal laser scanning microscopy and electron microscopy fitted with a focused ion beam and an energy-dispersive X-ray detector. Three materials were analysed: Two types of silica gel and one calcium phosphate. The results show that by combining the two methods it is possible to deduce the spatial distribution of the grafted cyclodextrins. Silica gel with small pores could be grafted to a depth of approximately 10 μm, whereas calcium phosphate with larger pores indicated a penetration depth larger than 30 μm. |
| Databáze: | OpenAIRE |
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