S-glycosides in medicinal chemistry: Novel synthesis of cyanoethylene thioglycosides and their pyrazole derivatives

Autor:	Ayman B. Farag, Nahed M. Fathy, Galal H. Elgemeie, Wafaa A. Zaghary
Rok vydání:	2017
Předmět:	chemistry.chemical_classification Magnetic Resonance Spectroscopy 010405 organic chemistry Chemistry Sodium Chemistry Pharmaceutical chemistry.chemical_element Glycoside Salt (chemistry) General Medicine Chemistry Techniques Synthetic Pyrazole Ethylenes 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound Thioglycosides Genetics Molecular Medicine Organic chemistry Pyrazoles Glycosides
Zdroj:	Nucleosides, nucleotidesnucleic acids. 36(3)
ISSN:	1532-2335
Popis:	A one-pot reaction of a sodium 2-cyanoethylene-1-thiolate salt with 2,3,4,6-tetra-O-acetyl-α-D-gluco- and galactopyranosyl bromides affords a new class of cyanoethylene thioglycosides. The conversion to the corresponding 5-aminopyrazoles confirms the E-configuration of these cyanoethylene thioglycosides.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691ac382fdcaa77878dd2d903d332a2a https://pubmed.ncbi.nlm.nih.gov/28045592 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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