Loxoprofen--another NSAID associated with acute asthmatic death
| Autor: | Masahiko Morita, Jun‐ichi Azumi, Noriko Tabata, Kumiko Sakata, Masakatsu Sakata, Koichi Itaya, Ritsuko Shimabukuro, Toshifumi Watanabe |
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| Rok vydání: | 1993 |
| Předmět: |
Drug
Male Allergy Chromatography Gas Health Toxicology and Mutagenesis Sodium media_common.quotation_subject chemistry.chemical_element Pharmacology Toxicology Gas Chromatography-Mass Spectrometry Therapeutic index Immunopathology medicine Humans Tissue Distribution Asthma media_common Phenylpropionates business.industry Anti-Inflammatory Agents Non-Steroidal Loxoprofen Middle Aged medicine.disease chemistry Toxicity business medicine.drug |
| Zdroj: | Journal of toxicology. Clinical toxicology. 31(2) |
| ISSN: | 0731-3810 |
| Popis: | Loxoprofen sodium (sodium 2[4-(2-oxocyclopentylmethyl) phenyl] dehydrate; CAS #68767-14-6) is a nonsteroidal, inflammatory drug marketed only in Japan. A case report describes its association with an acute asthmatic death with features resembling those evoked by similar drugs. The analytic methodology is reported. The blood levels of loxoprofen were in the therapeutic range. The tissue concentrations are reported. |
| Databáze: | OpenAIRE |
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