Accelerated decline in Helicobacter pylori seroprevalence rate during the screen and treat project in Vammala, Finland, as demonstrated in 29- to 45-year-old pregnant women

Autor: Seppo Sarna, Pentti Koskela, Timo U. Kosunen, Leena Rehnberg-Laiho, Anniina Salomaa, Hilpi Rautelin
Rok vydání: 2004
Předmět:
Zdroj: APMIS. 112:34-38
ISSN: 1600-0463
0903-4641
DOI: 10.1111/j.1600-0463.2004.apm1120106.x
Popis: The potential preventability of serious helicobacter-associated diseases - especially gastric cancer - has evoked interest in eradicating this pathogen from the population. We assessed the efficacy of the pioneering screen and treat intervention project in Vammala by studying helicobacter seroprevalence in pregnant women representing the normal population. Consecutive maternity clinic samples from native Finnish females at five different localities in 1995 (n=701) and 2000 (n=772) were investigated for class IgG H. pylori antibodies by enzyme immunoassay (Pyloriset EIA-G III, Orion Diagnostica, Espoo, Finland). In Vammala the change in helicobacter seroprevalence was -13%-units (between 1995 and 2000; p=0.0125, chi-square test) in > or =29-year-old females, +1.6%-units (difference statistically non-significant) in
Databáze: OpenAIRE