An international multicenter retrospective study to survey the landscape of thrombectomy in the treatment of anterior circulation acute ischemic stroke: outcomes with respect to age
| Autor: | Aquilla S Turk, David Fiorella, Joey English, Italo Linfante, Adam S Arthur, Don Frei, Michael Kelly, Adnan H. Siddiqui, Ansaar T Rai, Lissa Peeling, Michael L Martini, J Mocco, Keith Woodward, Josser E Delgado Almandoz, Reade De Leacy, Ricardo A. Hanel, Blaise Baxter |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Internationality Clinical variables medicine.medical_treatment Large vessel Revascularization Brain Ischemia 03 medical and health sciences 0302 clinical medicine Modified Rankin Scale Surveys and Questionnaires medicine Humans Prospective Studies 030212 general & internal medicine Acute ischemic stroke Aged Retrospective Studies Thrombectomy Stent retriever Aged 80 and over business.industry Age Factors Retrospective cohort study General Medicine Middle Aged Stroke Treatment Outcome Emergency medicine Female Surgery Neurology (clinical) Ordered logit business 030217 neurology & neurosurgery |
| Zdroj: | Journal of NeuroInterventional Surgery. 12:115-121 |
| ISSN: | 1759-8486 1759-8478 |
| Popis: | BackgroundThrombectomy is an efficacious treatment for acute ischemic stroke (AIS). However, relatively few studies to date have specifically examined the impact and clinical implications of age on outcomes for thrombectomy in anterior AIS.ObjectiveTo provide a snapshot of patient metrics and outcomes with respect to age following thrombectomy for anterior AIS to supplement the current body of data for predictors of clinical outcomes in a real-world setting.MethodsData were collected for 20 consecutive patients with AIS treated with thrombectomy at 15 high-volume stroke centers across North America between 2015 and 2016. Patients with anterior occlusions were dichotomized based on whether they were older or younger than 80 years. Ordinal logistic regression analyzed how clinical variables impacted disability using 90-day modified Rankin Scale (mRS) scores.ResultsAdequate revascularization (TICI ≥2B) was achieved in 92.3% of patients aged ConclusionThis analysis affirms age is a significant determinant of 90-day mRS scores following thrombectomy for large vessel anterior AIS. Further investigation into risks faced by elderly patients during thrombectomy may provide actionable information to help refine patient selection and improve outcomes. |
| Databáze: | OpenAIRE |
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