Photo-induced spin switching in a modified anthraquinone modulated by DNA binding
| Autor: | Giovanni Ribaudo, Antonio Toffoletti, Donatella Carbonera, Giuseppe Zagotto, Marco Bortolus |
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| Rok vydání: | 2019 |
| Předmět: |
Spin states
Intercalation (chemistry) Anthraquinones 010402 general chemistry Photochemistry 01 natural sciences law.invention law Molecule Physics::Chemical Physics Physical and Theoretical Chemistry Electron paramagnetic resonance Spin (physics) Density Functional Theory Quantitative Biology::Biomolecules Binding Sites Molecular Structure 010405 organic chemistry Chemistry Electron Spin Resonance Spectroscopy DNA Photochemical Processes 0104 chemical sciences Photoexcitation Excited state sense organs Ground state |
| Zdroj: | Photochemical & Photobiological Sciences. 18:2199-2207 |
| ISSN: | 1474-9092 1474-905X |
| DOI: | 10.1039/c8pp00586a |
| Popis: | An anthraquinone modified with a nitroxide radical and able to intercalate into DNA has been synthesized to obtain a molecule the spin state of which can be manipulated by visible light and DNA binding. The doublet ground state of the molecule can be photo-switched to either a strongly coupled spin state (quartet + doublet), when isolated, or to an uncoupled spin state (triplet and doublet), when bound to DNA. The different spin state that is obtained upon photoexcitation depends on the intercalation of the quinonic core into double-stranded DNA which changes the conformation of the molecule, thereby altering the exchange interaction between the excited state localized on the quinonic core and the nitroxide radical. The spin state of the system has been investigated using both continuous-wave and time-resolved EPR spectroscopy. |
| Databáze: | OpenAIRE |
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