The effect of permanganate on the ultraviolet absorption spectra of aromatic amino acids and proteins
| Autor: | John R. Loofbourow, Ward J. Haas, Irwin W. Sizer |
|---|---|
| Rok vydání: | 1950 |
| Předmět: |
chemistry.chemical_classification
biology Absorption spectroscopy Chemistry Spectrum Analysis Inorganic chemistry Permanganate Proteins Oxides Phenylalanine General Medicine Amino acid Amino Acids Aromatic Potassium permanganate chemistry.chemical_compound Manganese Compounds Potassium Permanganate Pepsin biology.protein Aromatic amino acids Amino Acids Tyrosine Nuclear chemistry |
| Zdroj: | Biochimica et Biophysica Acta. 6:601-605 |
| ISSN: | 0006-3002 |
| DOI: | 10.1016/0006-3002(50)90136-3 |
| Popis: | 1. 1. The effects of permanganate oxidation on the 293° K and 77° K ultraviolet absorption spectra of the aromatic amino acids and crystalline insulin and pepsin have been studied. 2. 2. The susceptibility of tyrosine and tryptophane, and the relative resistance of phenylalanine, to permanganate oxidation have been confirmed. 3. 3. Spectroscopic evidence was obtained for the formation of dopa in solutions of tyrosine, and of dopa groups in solutions of insulin and pepsin, by permanganate treatment. 4. 4. Permanganate induced changes in the fine structure of insulin and pepsin absorption spectra at 77° K are shown to parallel in several respects the spectrum changes in tyrosine and tryptophane similarly treated. |
| Databáze: | OpenAIRE |
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