Two maternally derived missense mutations in the tyrosine kinase domain of the RET protooncogene in a patient with de novo MEN 2B
| Autor: | Samuel A. Wells, N J Scavarda, Paul J. Goodfellow, Charles E. Jackson, Yutaka Kitamura |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Ret gene Molecular Sequence Data Restriction Mapping Multiple Endocrine Neoplasia Type 2b Biology medicine.disease_cause Polymerase Chain Reaction Proto-Oncogene Proteins Proto-Oncogenes Genetics medicine Drosophila Proteins Humans Point Mutation Missense mutation RET PROTOONCOGENE Deoxyribonucleases Type II Site-Specific Molecular Biology Genetics (clinical) DNA Primers Mutation Base Sequence Proto-Oncogene Proteins c-ret Receptor Protein-Tyrosine Kinases General Medicine medicine.disease Pedigree Cancer research Female MULTIPLE ENDOCRINE NEOPLASIA TYPE II Tyrosine kinase Multiple endocrine neoplasia type 2b |
| Zdroj: | Human Molecular Genetics. 4:1987-1988 |
| ISSN: | 1460-2083 0964-6906 |
| DOI: | 10.1093/hmg/4.10.1987 |
| Databáze: | OpenAIRE |
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