Biofilms of clinical strains ofStaphylococcusthat do not contain polysaccharide intercellular adhesin

6)-beta-D-glucosamine and teichoic acid. In the present paper we show that, unlike this model strain, certain clinical isolates of coagulase-negative staphylococci produce biofilms that do not contain detectable amounts of poly-N-acetyl-(1-->6)-beta-D-glucosamine. In contrast to that of S. epidermidis RP62A, these biofilms are not detached with metaperiodate, while proteinase K causes their partial dispersal. -->

ISSN:	1574-6968 0378-1097
DOI:	10.1111/j.1574-6968.2005.00043.x
Přístupová URL adresa:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690b29c6f0709f5c2dc09b609cf9eae7 https://doi.org/10.1111/j.1574-6968.2005.00043.x
Rights:	OPEN
Přírůstkové číslo:	edsair.doi.dedup.....690b29c6f0709f5c2dc09b609cf9eae7
Autor:	Saïd Jabbouri, Irina Sadovskaya, Philippe Chaignon, Grigorij Kogan, Ali Chokr
Rok vydání:	2006
Předmět:	chemistry.chemical_classification Teichoic acid Strain (chemistry) Staphylococcus Polysaccharides Bacterial Biofilm Biology medicine.disease_cause biology.organism_classification Proteinase K Polysaccharide Microbiology chemistry.chemical_compound chemistry Staphylococcus epidermidis Staphylococcus aureus Biofilms Genetics medicine biology.protein Humans Molecular Biology
Zdroj:	FEMS Microbiology Letters. 255:11-16
ISSN:	1574-6968 0378-1097
DOI:	10.1111/j.1574-6968.2005.00043.x
Popis:	Staphylococcus aureus and coagulase-negative staphylococci, primarily Staphylococcus epidermidis, are recognized as a major cause of nosocomial infections associated with the use of implanted medical devices. The capacity of S. epidermidis to form biofilms, allowing it to evade host immune defence mechanisms and antibiotic therapy, is considered to be crucial in colonizing the surfaces of medical implants and dissemination of infection. It has previously been demonstrated that the biofilm of a model strain S. epidermidis RP62A comprises two carbohydrate-containing moieties, a polysaccharide having a structure of a linear poly-N-acetyl-(1-->6)-beta-D-glucosamine and teichoic acid. In the present paper we show that, unlike this model strain, certain clinical isolates of coagulase-negative staphylococci produce biofilms that do not contain detectable amounts of poly-N-acetyl-(1-->6)-beta-D-glucosamine. In contrast to that of S. epidermidis RP62A, these biofilms are not detached with metaperiodate, while proteinase K causes their partial dispersal.
Databáze:	OpenAIRE
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