Successful Treatment of Two Brothers with Congenital Afibrinogenemia for Splenic Rupture Using Heat- and Solvent Detergent-Treated Fibrinogen Concentrates
| Autor: | Midori Shima, Hiromichi Kanehiro, Akira Yoshioka, Yoshikatsu Sawamoto, John C. Giddings, Akira Nishimura, Naoki Matsuo, Ichiro Tanaka |
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| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Hot Temperature Adolescent Detergents Spleen Computed tomography Fibrinogen medicine Coagulopathy Humans Solvent detergent Child Afibrinogenemia medicine.diagnostic_test business.industry Anticoagulants Splenic Rupture Hematology medicine.disease Surgery Congenital afibrinogenemia medicine.anatomical_structure Oncology Pediatrics Perinatology and Child Health Solvents Tomography X-Ray Computed Complication business Follow-Up Studies medicine.drug |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 19:462-465 |
| ISSN: | 1077-4114 |
| Popis: | This report describes life-threatening spontaneous splenic rupture in two brothers with congenital afibrinogenemia.Two brothers, aged 11 and 14 years, had intra-abdominal bleeding due to splenic rupture confirmed by ECHO ultrasonography and computed tomography scans.Splenectomy was performed after administration of heat- and solvent-detergent treated fibrinogen concentrates.Hemostatic treatment for splenic rupture using heat- and solvent detergent-treated fibrinogen concentrates was effective. Careful attention must be paid to the risk of splenic rupture during the growth spurt in physically active children with this rare coagulation disorder. |
| Databáze: | OpenAIRE |
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