Assessment of flow profile of left anterior descending coronary artery in hypertrophic cardiomyopathy by transesophageal pulsed Doppler echocardiography
| Autor: | Hiroyuki Matsuzaki, Yuichiro Wasaki, Takashi Tone, Nobuaki Tanaka, Junko Hiro, Tetsuzo Takahashi, Masunori Matsuzaki, Kazuyoshi Okada, Hideo Shimizu, Yasuaki Tomochika |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart disease Diastole Hemodynamics Anterior Descending Coronary Artery Coronary Circulation Internal medicine medicine Humans Aged business.industry Hypertrophic cardiomyopathy Pulsed Doppler Echocardiography Blood flow Cardiomyopathy Hypertrophic Middle Aged medicine.disease Coronary Vessels Echocardiography Doppler Flow velocity cardiovascular system Cardiology Female Cardiology and Cardiovascular Medicine business Blood Flow Velocity Echocardiography Transesophageal |
| Zdroj: | The American Journal of Cardiology. 72:1425-1430 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/0002-9149(93)90191-e |
| Popis: | This study assessed the flow velocity profiles of the left anterior descending coronary artery (LAD) in 7 patients with nonobstructive hypertrophic cardiomyopathy (HC) and in 6 normal subjects by transesophageal pulsed Doppler echocardiography, and evaluated their characteristics and the hemodynamic determinants. Systolic peak flow velocity of the LAD (7 +/- 30 cm/sec) was significantly lower in patients with HC than in normal subjects (34 +/- 11 cm/s, p0.05), and there was a significant inverse correlation between systolic peak flow velocity and the thickness of the ventricular septum (r = 0.81, p0.01). In 2 cases of HC with ventricular septal thickness of20 mm, a remarkable systolic reverse flow was observed in the LAD. However, there was no significant difference in diastolic peak flow velocity between HC and normal subjects. During early diastole, the acceleration time of LAD flow velocity was significantly prolonged (210 +/- 67 vs 95 +/- 15 ms, p0.01) and the acceleration rate was significantly decreased (3.6 +/- 2.0 vs 6.6 +/- 1.8 m/s2, p0.02) in patients with HC. The time constant of the left ventricular pressure decay was significantly prolonged in patients with HC (55 +/- 6 ms) compared with normal subjects (39 +/- 2 ms, p0.001). In HC, increased intramural perivascular pressure of the thickened ventricular septum during systole may be attributed to systolic LAD flow pattern. However, the early and mid-diastolic LAD flow pattern may be affected by impaired left ventricular relaxation. |
| Databáze: | OpenAIRE |
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