Terminal T-wave inversion predicts reperfusion tachyarrhythmias in STEMI

Autor:	Ksenia A, Sedova, Marina M, Demidova, Jan E, Azarov, Jan, Hejda, Jonas, Carlson, Olesya G, Bernikova, Natalia, Arteyeva, David, Erlinge, Pyotr G, Platonov
Rok vydání:	2022
Předmět:	Male Middle Aged Electrocardiography Percutaneous Coronary Intervention Tachycardia Reperfusion Ventricular Fibrillation Humans ST Elevation Myocardial Infarction Female Cardiology and Cardiovascular Medicine Anterior Wall Myocardial Infarction Aged Retrospective Studies
Zdroj:	Journal of Electrocardiology. 71:28-31
ISSN:	0022-0736
DOI:	10.1016/j.jelectrocard.2021.12.008
Popis:	A reliable electrocardiographic predictor of ventricular fibrillation (VF) in patients with ST elevation myocardial infarction (STEMI) is lacking so far. Previous experimental/simulation study suggested a terminal T-wave inversion (TTWI) in ischemia-related ECG leads corresponding to anterior infarct localization as an independent predictor of reperfusion VF (rVF). This T-wave characteristic has never been tested as a rVF predictor in clinical settings. The aim of this study was to test if terminal T-wave inversion (TTWI) at admission ECG (before reperfusion) can serve as a predictor of ventricular fibrillation during reperfusion (rVF) in patients with anterior STEMI undergoing primary PCI.Study population included consecutive patients with anterior infarct localization admitted for primary PCI (n = 181, age 65 [57; 76] years, 66% male). Of those, 14 patients had rVF (rVF group, age 59 [47; 76] years, 64% male) and patients without rVF comprised the No-rVF group (n = 167, age 65 [57; 76] years, 66% male). Association of TTWI with rVF was analyzed using logistic regression analysis adjusted for relevant clinical and electrocardiographic covariates. The prevalence of TTWI in rVF group was 62% comparing to 23% in the No-rVF group, p = 0.005. TTWI was associated with increased risk of rVF (OR 5.51; 95% CI 1.70-17.89; p = 0.004) and remained a significant predictor after adjustment for age, gender, history of MI prior to index admission, VF before reperfusion, TThe terminal T-wave inversion in anterior leads before PCI independently predicted rVF in patients with anterior MI thus confirming the previous experimental/simulation findings.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6902fa8e5e2c69638ba0a81035226fc4 https://doi.org/10.1016/j.jelectrocard.2021.12.008 Zobrazit plný text záznamu Full Text from ScienceDirect