Facultative cheating supports the coexistence of diverse quorum-sensing alleles
| Autor: | Ishay Ben-Zion, Avigdor Eldar, Valeria Lipsman, Eran Even-Tov, Tasneem Bareia, Shira Omer-Bendori, Shaul Pollak |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Genetics Facultative Multidisciplinary genetic structures biology Obligate Cheating fungi 030106 microbiology Quorum Sensing Bacillus subtilis Kin selection Biological Sciences biology.organism_classification Models Biological Intraspecific competition 03 medical and health sciences Quorum sensing Autoinducer |
| Zdroj: | Proceedings of the National Academy of Sciences. 113:2152-2157 |
| ISSN: | 1091-6490 0027-8424 |
| DOI: | 10.1073/pnas.1520615113 |
| Popis: | Bacterial quorum sensing enables bacteria to cooperate in a density-dependent manner via the group-wide secretion and detection of specific autoinducer molecules. Many bacterial species show high intraspecific diversity of autoinducer-receptor alleles, called pherotypes. The autoinducer produced by one pherotype activates its coencoded receptor, but not the receptor of another pherotype. It is unclear what selection forces drive the maintenance of pherotype diversity. Here, we use the ComQXPA system of Bacillus subtilis as a model system, to show that pherotype diversity can be maintained by facultative cheating--a minority pherotype exploits the majority, but resumes cooperation when its frequency increases. We find that the maintenance of multiple pherotypes by facultative cheating can persist under kin-selection conditions that select against "obligate cheaters" quorum-sensing response null mutants. Our results therefore support a role for facultative cheating and kin selection in the evolution of quorum-sensing diversity. |
| Databáze: | OpenAIRE |
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