Virulence of Newcastle disease virus: what is known so far?
| Autor: | Peter J. M. Rottier, Guus Koch, J. C. F. M. Dortmans, Ben Peeters |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
animal structures
Virulence Factors Newcastle Disease animal diseases viruses Newcastle disease virus matrix protein Virulence Review Biology medicine.disease_cause Genome Newcastle disease Virus nucleotide-sequence cleavage-site influenza-a virus Influenza A virus medicine fusion protein Animals strand rna viruses Gene Poultry Diseases paramyxovirus-v-proteins lcsh:Veterinary medicine General Veterinary biochemical phenomena metabolism and nutrition biology.organism_classification Virology veterinary(all) Reverse genetics Virology & Molecular Biology Virologie & Moleculaire Biologie vesicular stomatitis-virus pigeon pmv-1 viruses Vesicular stomatitis virus embryonic structures hemagglutinin-neuraminidase protein lcsh:SF600-1100 Chickens |
| Zdroj: | Veterinary Research, 42(1) Veterinary Research Veterinary Research 42 (2011) 1 Veterinary Research, Vol 42, Iss 1, p 122 (2011) |
| ISSN: | 0928-4249 |
| DOI: | 10.1186/1297-9716-42-122 |
| Popis: | In the last decade many studies have been performed on the virulence of Newcastle disease virus (NDV). This is mainly due to the development of reverse genetics systems which made it possible to genetically modify NDV and to investigate the contribution of individual genes and genome regions to its virulence. However, the available information is scattered and a comprehensive overview of the factors and conditions determining NDV virulence is lacking. This review summarises, compares and discusses the available literature and shows that virulence of NDV is a complex trait determined by multiple genetic factors. |
| Databáze: | OpenAIRE |
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