Calcium movement of sarcoplasmic reticulum from hindlimb suspended muscle
| Autor: | Toshitada Yoshioka, Katsumasa Yamashita-Goto, Takuhiko Shirota, Takashi Tazoe |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
Aerospace Engineering chemistry.chemical_element Hindlimb Calcium Caffeine medicine Animals Rats Wistar Muscle Skeletal Weightlessness Simulation Weightlessness musculoskeletal neural and ocular physiology Endoplasmic reticulum Hindlimb Suspension musculoskeletal system Rats Sarcoplasmic Reticulum Muscle Fibers Slow-Twitch chemistry Muscle Fibers Fast-Twitch Biophysics Central Nervous System Stimulants Contracture medicine.symptom tissues Muscle Contraction |
| Zdroj: | Acta Astronautica. 38:209-212 |
| ISSN: | 0094-5765 |
| DOI: | 10.1016/0094-5765(96)00010-0 |
| Popis: | The function of the sarcoplasmic reticulum (SR) was examined in the slow soleus and fast extensor digitorum longus (EDL) muscles of rats submitted to 14 days of weightlessness produced by hindlimb suspension (HS). Ca2+ uptake, Ca2+ release and passive Ca2+ leakage through the SR membrane were investigated using a method of caffeine-induced contracture on the single mechanically skinned fibers. In the SR of suspended soleus muscles, the rate of Ca2+ uptake was higher than in the control muscles. However, there was no difference between the suspended and control muscles in the rate of Ca2+ uptake of the SR in EDL after HS. In soleus muscles, Ca2+ movements of the SR from the suspended muscle acquired the properties that were similar to those of the control fast muscle. The study of Ca2+ leakage showed that the velocity and amount of passive Ca2+ leakage from SR in soleus and EDL were apparently increased after HS. The results suggested that the functional properties of the SR membrane in slow and fast muscles were changed after HS. |
| Databáze: | OpenAIRE |
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