A New Heliquinomycin Analogue with Immunosuppressive Activity from Streptomyces sp. jys28
| Autor: | Chenggang Zou, Yongjiang Wang, Sheng-Xiong Huang, Wensheng Xiang, Can Su, Chong-Xi Liu |
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| Rok vydání: | 2019 |
| Předmět: |
heliquinomycin
Pharmacology biology Chemistry Organic Chemistry immunosuppressive activity Plant Science Heliquinomycin biology.organism_classification Streptomyces lcsh:QK1-989 Microbiology lcsh:Chemistry lcsh:QD241-441 antibacterial activity lcsh:QD1-999 lcsh:Organic chemistry lcsh:Botany Drug Discovery |
| Zdroj: | Records of Natural Products, Vol 13, Iss 6, Pp 456-461 (2019) |
| ISSN: | 1307-6167 |
| DOI: | 10.25135/rnp.123.18.12.1085 |
| Popis: | Heliquinomycin (1) and a new analogue 9′-methoxy-heliquinomycin (2) were isolated from the culture broth of Streptomyces sp. jys28. The structure of new analogue was elucidated by comprehensive analyses of HR-ESI-MS and NMR spectroscopic data. Among them, Heliquinomycin (1) showed immunosuppressive and antibacterial activities. |
| Databáze: | OpenAIRE |
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