Effects of rAAV sox9 gene transfer upon the chondrogenic differentiation of hMSCs seeded in polyurethane scaffolds

Autor:	Venkatesan, JK, Rey-Rico, A, Gardner, O, Eglin, D, Alini, M, Stoddart, M, Cucchiarini, M, Madry, H
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	endocrine system Cartilage ddc: 610 Tissue Engineering Gene Therapy 610 Medical sciences Medicine Regenerative Medicine
Zdroj:	Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2015); 20151020-20151023; Berlin; DOCPO11-97 /20151005/
DOI:	10.3205/15dkou551
Popis:	Objectives: Implantation of genetically modified MSCs with polyurethane (PU) scaffolds is an attractive tool to treat articular cartilage defects. Here we evaluated whether rAAV sox9 gene transfer in hMSCs seeded onto PU scaffolds enhances the chondrogenic differentiation processes in dynamic culture[for full text, please go to the a.m. URL] Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2015)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d66a97c2cf53d1bcdd225d588f9110 Zobrazit plný text záznamu