The seroepidemiology of herpes simplex virus type 1 and 2 in Europe
| Autor: | Mira Kojouharova, R. Vranckx, P Teocharov, Nina Gatcheva, K Roubalova, Guido François, B. Kriz, Wiebke Hellenbrand, Robin Gopal, W. Thierfelder, Richard Pebody, I Klavs, T Kortbeek, Katarina Prosenc, Nick Andrews, Sari Jokinen, H.E. de Melker, P. Van Damme, David Brown, M. Valle |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Sexually transmitted disease medicine.medical_specialty Adolescent Cross-sectional study Herpesvirus 2 Human viruses Herpesvirus 1 Human Dermatology Serology law.invention Age Distribution law Epidemiology medicine Humans Seroprevalence Sex Distribution Young adult Child Aged business.industry Public health Infant Herpes Simplex Middle Aged Virology Europe Cross-Sectional Studies Infectious Diseases Transmission (mechanics) Child Preschool Female Original Article sense organs business Demography |
| Zdroj: | Sexually transmitted infections |
| ISSN: | 1368-4973 |
| DOI: | 10.1136/sti.2003.005850 |
| Popis: | Objectives: To describe the seroepidemiology of herpes simplex virus (HSV) types 1 and 2 in the general populations of eight European countries to better understand recent reported changes in disease epidemiology. Methods: Belgium, Bulgaria, Czech Republic, England and Wales, Finland, Germany, Netherlands, and Slovenia conducted national cross sectional serological surveys for HSV-1 and HSV-2 between 1989 and 2000. Survey sizes ranged from 3000 to 7166 sera. External quality control was ensured through reference panel testing. Results: Large intercountry and intracountry differences in HSV-1 and HSV-2 seroprevalence were observed. Age standardised HSV-1 seroprevalence ranged from 52% in Finland, to 57% in the Netherlands, 67% in Belgium, 81% in Czech Republic, and 84% in Bulgaria. Age standardised (>12 years) HSV-2 seroprevalence ranged from 24% in Bulgaria, to 14% in Germany, 13% in Finland, 11% in Belgium, 9% in Netherlands, 6% in Czech Republic, and 4% in England and Wales. In all countries, probability of seropositivity for both infections increased with age. A large proportion of teenagers and young adults remain HSV-1 susceptible particularly in northern Europe. Women were significantly more likely to be HSV-2 seropositive in six of seven (p |
| Databáze: | OpenAIRE |
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