Prognostic Factors and Recurrence of Small Hepatocellular Carcinoma after Hepatic Resection or Microwave Ablation: A Retrospective Study
| Autor: | Zhi Li Wang, De Jiang Yu, Xiao Ling Yu, Ping Liang, Bao Wei Dong |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Vascular Endothelial Growth Factor A Oncology medicine.medical_specialty Carcinoma Hepatocellular C-Met Multivariate analysis Disease-Free Survival Metastasis chemistry.chemical_compound Internal medicine medicine Humans Retrospective Studies business.industry Proportional hazards model Liver Neoplasms Microwave ablation Gastroenterology Cell Differentiation Retrospective cohort study Middle Aged Proto-Oncogene Proteins c-met Prognosis medicine.disease Immunohistochemistry Survival Analysis digestive system diseases chemistry Hepatocellular carcinoma Multivariate Analysis Catheter Ablation Female Fibroblast Growth Factor 2 Surgery Neoplasm Recurrence Local business |
| Zdroj: | Journal of Gastrointestinal Surgery. 12:327-337 |
| ISSN: | 1873-4626 1091-255X |
| DOI: | 10.1007/s11605-007-0310-0 |
| Popis: | This study aims to analyze the long-term therapeutic results of small HCC less than 5 cm in diameter after microwave ablation (MA) or hepatic resection (HR) and choose factors that could predict metastasis and recurrence of small HCC. The metastasis and recurrence of 194 patients with one HCC less than 5 cm in diameter who underwent curative HR or MA between January 1995 and December 2004 were reviewed retrospectively; immunohistochemistry was used to analyze the expressions of VEGF, bFGF, and c-Met in HCC tissues. Posttreatment prognostic factors were evaluated by multivariate analysis using Cox’s proportional hazards model. The variables included the expressions of these three proteins in HCC tissues, the clinical and pathologic characteristics of the patients. The retrospective study showed that 1-, 3-, and 5-year disease-free survival rates of patients with single HCC of diameter |
| Databáze: | OpenAIRE |
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