Nomenclature and diagnosis of gluten-related disorders: A position statement by the Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO)
| Autor: | Massimo Bellini, Renato Cannizzaro, Nicoletta Pellegrini, Danilo Villalta, Donatella Barisani, Carolina Tomba, Gioacchino Leandro, Antonio Carroccio, Maria Teresa Bardella, Leda Roncoroni, Marco Soncini, Luca Elli, Stefano Ferrero, Flavio Valiante |
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| Přispěvatelé: | Elli L., Villalta D., Roncoroni L., Barisani D., Ferrero S., Pellegrini N., Bardella M.T., Valiante F., Tomba C., Carroccio A., Bellini M., Soncini M., Cannizzaro R., Leandro G., Elli, L, Villalta, D, Roncoroni, L, Barisani, D, Ferrero, S, Pellegrini, N, Bardella, M, Valiante, F, Tomba, C, Carroccio, A, Bellini, M, Soncini, M, Cannizzaro, R, Leandro, G |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty Settore MED/09 - Medicina Interna Glutens Non-celiac gluten sensitivity Wheat Hypersensitivity Disease Gastroenterology Diagnosis Differential Diet Gluten-Free Hospital 03 medical and health sciences 0302 clinical medicine Risk Factors Food allergy celiac disease wheat allergy non-celiac gluten sensitivity gluten-related disorders food allergy Gluten-related disorder Internal medicine medicine Humans 030212 general & internal medicine Risk factor Societies Medical chemistry.chemical_classification Hepatology business.industry Risk Factor Incidence (epidemiology) BIO/13 - BIOLOGIA APPLICATA nutritional and metabolic diseases Evidence-based medicine medicine.disease Gluten Hospitals Wheat allergy digestive system diseases Celiac Disease Italy chemistry 030211 gastroenterology & hepatology Differential diagnosis business Human |
| Popis: | Background “Gluten-related disorders” is a term that encompasses different diseases induced by the ingestion of gluten-containing food. Because of their incidence the scientific community has been intensively studying them. Aim To support gastroenterologists with a correct nomenclature and diagnostic approach to gluten-related disorders in adulthood. Methods The Italian Association of Hospital Gastroenterologists and Endoscopists (AIGO) commissioned a panel of experts to prepare a position statement clarifying the nomenclature and diagnosis of gluten-related disorders, focusing on those of gastroenterological interest. Each member was assigned a task and levels of evidence/recommendation have been proposed. Results The panel identified celiac disease, wheat allergy and non-celiac gluten sensitivity as the gluten-related disorders of gastroenterological interest. Celiac disease has an autoimmune nature, wheat allergy is IgE-mediated while the pathogenesis of non-celiac gluten sensitivity is still unknown as is the case of non-IgE mediated allergy. Diagnosis should start with the serological screening for celiac disease and wheat allergy. In case of normal values, the response to a gluten-free diet should be evaluated and a confirmatory blind food challenge carried out. Conclusions Gluten-related disorders are clinically heterogeneous. Patients should be carefully managed and specific protocols applied for a correct differential diagnosis in gastroenterological setting. |
| Databáze: | OpenAIRE |
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