Identification of the novel synthetic cannabimimetic 8-quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate (QMPSB) and other designer drugs in herbal incense
| Autor: | Katrina Goodchild, Sarah J. Atkinson, Karen Blakey, Sue E. Boyd, Jenny McGowan, Pim M. Slottje, Jenna Wolf |
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| Rok vydání: | 2015 |
| Předmět: |
Magnetic Resonance Spectroscopy
Injury control medicine.drug_class Poison control 01 natural sciences Benzoates Gas Chromatography-Mass Spectrometry Mass Spectrometry Incense Pathology and Forensic Medicine Designer Drugs Toxicology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Smoke medicine Organic chemistry Humans 030216 legal & forensic medicine Indole test Sulfonamides Ethanol Chemistry Cannabinoids 010401 analytical chemistry Ethyl ester 0104 chemical sciences Designer drug Methanol Law Chromatography Liquid |
| Zdroj: | Forensic science international. 260 |
| ISSN: | 1872-6283 |
| Popis: | The identification and structural elucidation of the novel synthetic cannabimimetic 8-quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate (QMPSB) by GC-MS, LC-MS and NMR is reported. QMPSB was identified in Queensland, Australia on plant material packaged as herbal incense. The identification of QMPSB was initially hampered due to trans-esterification occurring in the extraction solvent. An investigation of the trans-esterification of QMPSB in methanol and ethanol was conducted and analytical data for the respective methyl and ethyl esters are reported. Analytical data is presented for two other compounds detected on seized plant material packaged as herbal incense: the synthetic cannabimimetic 1-[(N-methylpiperidin-2-yl)methyl]-3-(4-methyl-1-naphthoyl)indole (MAM-1220) and the JWH-081 analogue 1-(cyclohexylmethyl)-3-(4-methoxy-1-naphthoyl)indole (CHM-081). |
| Databáze: | OpenAIRE |
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